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cd62l bv421  (Alomone Labs)


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    Alomone Labs cd62l bv421
    Cd62l Bv421, supplied by Alomone Labs, used in various techniques. Bioz Stars score: 93/100, based on 14 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cd62l bv421/product/Alomone Labs
    Average 93 stars, based on 14 article reviews
    cd62l bv421 - by Bioz Stars, 2026-02
    93/100 stars

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    A) Relative proportions of naive/memory CD4 + and CD8 + T-cell subsets for CAR+ cells engineered via hydropore (Hy-CAR-T) or nucleofection (Nuc-CAR-T). Percentages of naive/memory cells for both CD4 + and CD8 + T-cells were calculated based on expression of CD45RA and CD62L. B) Heatmap of 40 proteins secreted by CAR-T cells that were significantly differentially expressed compared to WT cells in the presence of NALM6 target cells. C) Comparison of cytokine secretion patterns of CAR-T cells from donor 1 and donor 2 generated using either nucleofection or hydroporation upon activation with NALM6 target cells at a 1:1 ratio, as assessed by 187-plex nELISA. NS: not significant; FC: fold-change.

    Journal: bioRxiv

    Article Title: Scalable intracellular delivery via microfluidic vortex shedding enhances the function of chimeric antigen receptor T-cells

    doi: 10.1101/2024.06.25.600671

    Figure Lengend Snippet: A) Relative proportions of naive/memory CD4 + and CD8 + T-cell subsets for CAR+ cells engineered via hydropore (Hy-CAR-T) or nucleofection (Nuc-CAR-T). Percentages of naive/memory cells for both CD4 + and CD8 + T-cells were calculated based on expression of CD45RA and CD62L. B) Heatmap of 40 proteins secreted by CAR-T cells that were significantly differentially expressed compared to WT cells in the presence of NALM6 target cells. C) Comparison of cytokine secretion patterns of CAR-T cells from donor 1 and donor 2 generated using either nucleofection or hydroporation upon activation with NALM6 target cells at a 1:1 ratio, as assessed by 187-plex nELISA. NS: not significant; FC: fold-change.

    Article Snippet: From these, we gated on CD4 + (BUV395, BD Biosciences,CAT#563550) and CD8 + (BV711, BD Biosciences, CAT#569389) T-cells and further divided those into four populations based on their expression of CD45RA (BB515, BD Biosciences, CAT#564552) and CD62L (BV421, BD Biosciences, CAT#563862).

    Techniques: Expressing, Comparison, Generated, Activation Assay